Caldikind Plus Capsule 10
Uses :Calcitriol Calcitriol is an active metabolite of vitamin D, which is used to treat low levels of calcium that occurs due to conditions such as hypoparathyroidism, chronic renal dialysis, and plaque psoriasis. Calcium Calcium is essential for the human body for various purposes. Calcium can be taken together with Vitamin D to treat bone problems such as thinning of bones. In kidney failure patients, calcium helps to reduce the parathyroid hormone levels. Calcium is also used to treat the symptoms of premenstrual syndrome (PMS) (e.g. mood swings, pain, food cravings, bloating, etc.) in women. The salt form of calcium is used to treat indigestion problems and heartburn. Docosahexaenoic acid Docosahexaenoic acid taken with a proper diet helps in lowering the risk of age-related vision loss. It also reduces the risk of death in patients with coronary artery disease of the heart. Eicosapentaenoic acid Eicosapentaenoic acid is a fatty acid which is used along with other anti-depressants to treat depression. It helps in wound healing after surgery. The other eicosapentaenoic acid uses include treatment of psoriasis, certain mood disorders, and symptoms of menopause. It reduces the risk of stroke, heart attack, and death in people with clogged arteries of the heart. Boron Boron is a mineral found in food and other sources. It is used to developing strong bones, osteoarthritis, building muscles, testosterone levels, improves thinking skill, and muscle coordination. Additionally, to treat yeast infections in the vagina, astringent, and eye wash. Folic acid Folic acid is prescribed for the treatment of megaloblastic anemia, folic acid deficiency, and macrocytic anemia. It is used to treat and prevent folic acid deficiency diseases. It is prescribed during pregnancy to promote the development of the fetal brain and spinal cord. It prevents the birth defects such as spina bifida in the fetus. It prevents a colon cancer, cervical cancer, heart diseases, and stroke. It is prescribed to prevent memory loss in the patients with Alzheimer’s disease. Methylcobalamin Methylcobalamin is a form of vitamin B12 which is used to treat vitamin B12 deficiency. It is also used in the treatment of pernicious anemia. Vitamin B12 deficiency is seen in patients with fish tapeworm infestation, a malignancy of pancreas or bowel and folic acid deficiency.
Mode of drug action
Calcitriol Calcitriol promotes absorption of dietary calcium from the gastrointestinal tract and increases renal tubular reabsorption, thereby increasing blood calcium levels. It also promotes calcium release from bone cells. Calcium Calcium is an essential mineral for the formation of bones. The increase in the levels of calcium in the blood inhibits the parathyroid gland from secreting the parathyroid hormone. Calcium works by neutralizing the acid in the stomach. Correcting the calcium levels helps in the adequate release of chemical substances from the brain involved in regulating the ovarian hormones, thus, reducing PMS symptoms. Docosahexaenoic acid Docosahexaenoic acid is important for the development of tissues in the eyes and the nerves. It also works by lowering the levels of certain lipids in the blood and decreasing the thickness of the blood. Eicosapentaenoic acid Eicosapentaenoic acid works by preventing the blood from clotting easily. It reduces the pain and swelling. It also lowers the levels of lipids in the blood. Boron Boron helps to handle other minerals such as magnesium and phosphorus. It also increases estrogen levels in women and men. It helps to maintain healthy bones and mental condition. Folic acid Folic acid is required for the proper development of the body. It plays a major role in the formation of genetic material - DNA. Folic acid present in the dietary substances is in its inactive form. It is converted to tetrahydrofolic acid and methyltetrahydrofolate in the presence of the enzyme dihydrofolate reductase. Folic acid takes part in erythropoiesis and produces red blood cells. It also plays a role in the synthesis of nucleic acids. Folic acid along with vitamin B12 causes remethylation of homocysteine to methionine and helps to maintain the normal levels of homocysteine. Methylcobalamin Methylcobalamin or Vitamin B12 plays an important role in the cell growth, cell reproduction, hematopoiesis, and myelin synthesis (in the nerves). It works in conjugation with folic acid and enhances the synthesis of DNA. Vitamin B12 maintains the functions of bone marrow and enhances the production of red blood cells. It is also required for the metabolism of carbohydrate, fat, and protein. Deficiency of vitamin B12 can decrease the metabolism of folic acid and can lead to folic acid deficiency.
What are the common side effects?
Calcitriol The main side effect of calcitriol is hyperglycemia. Other effects include weakness, loss of appetite, metallic taste, nausea, vomiting, constipation, increased thirst, sweating, itching, and headache. Calcium The common side effects include belching, gas formation, bloating, and constipation. Docosahexaenoic acid The common side effects of docosahexaenoic acid are nausea, gas or bloating, bruising, and prolonged bleeding. Eicosapentaenoic acid The common side effects of eicosapentaenoic acid are nausea, diarrhea, skin rash, itching, heartburn, nosebleed, joint, muscle, and back pain. Boron The common side effects of boron are itching, high fever, and irritation, burning sensation, rash, hives, and sweating. Folic acid The common side effects reported by the individuals taking folic acid are fever, reddened skin, shortness of breath, skin rash or itching, tightness in chest, troubled breathing, wheezing, and general weakness or discomfort. Methylcobalamin The common side effects of methylcobalamin are stomach pain, bleeding from the gums or nose, bluish discoloration of the lips and fingernails, chest pain, cough, decreased urine output, difficulty in breathing, eye pain, fatigue, and increased heartbeat.
Pregnancy: Safe under medical guidance Breast feeding: Safe under medical guidance Alcohol: Unsafe Kidney dysfunction: Caution required Liver dysfunction: Caution required
Special precautions for safe use
• Consult the doctor immediately, if any side effects of Caldikind Plus such as headache, urinary tract infection, and abdominal pain are experienced.
• Before taking tab Caldikind Plus, inform the doctor about the current health conditions.
• Stop using Caldikind Plus tablet, if any allergic reactions are experienced.
• Avoid antacids while taking Caldikind Plus medicine.
• Pregnant or breastfeeding women should consult the doctor before using Caldikind Plus medication.
What else should I know?
1. Do I need to follow special dietary instructions while taking calcitriol? Yes. You need to take calcium rich foods, as the medication is effective only in the presence of adequate levels of calcium in the body. However, do not consume too much of calcium foods as excess intake may cause adverse effects.
2. Is calcitriol safe in pregnancy? No significant scientific data is present to determine the safe use of calcitriol in pregnancy. It is recommended to consult your doctor before taking the drug.
3. Is calcitriol same as vitamin D? Calcitriol is the active metabolite of vitamin D. Skin synthesizes plain form of vitamin D, which is metabolized into calcidiol in liver. In the kidney, calcidiol is further metabolized into calcitriol, the active metabolite.
4. I am experiencing a metallic taste in mouth and loss of appetite after taking calcitriol. Is that a common side effect? Loss of appetite and metallic taste are effects seen due to increased calcium levels in the blood due to the use of calcitriol. Your doctor may do a dose adjustment of calcitriol medication to subside these effects.
5. Can I take vitamin D supplements along with calcitriol? No. You should not take vitamin D supplements, multivitamins that contain vitamin D and foods containing vitamin D as this can lead to hypercalcemia. Calcium
1. I have low stomach acid levels. How should I take calcium tablets? Low levels of stomach acid can reduce the absorption of calcium. Therefore, you must take the tablets with meals to increase the absorption.
2. Can I take thyroid-stimulating medications along with calcium? Calcium can interfere with the thyroid medications. Therefore, take these drugs with a time gap of at least 4 hours.
3. Can I take antibiotics and calcium together? Absorption of some of the antibiotics gets lowered in the presence of calcium. Therefore, give a gap of at least 1 hour between taking the two drugs.
4. What is the dose of calcium for heartburn? Usually, 0.5-
1.5 grams of the antacid calcium carbonate helps to relieve heartburn. However, you must consult a doctor to know the right dose for you.
5. Should I take calcium tablets with food or without food? It is better to take calcium tablets with food to promote absorption of the medicine.
6. Can I take calcium tablets during pregnancy? Yes. It is safe to take the recommended doses of calcium during pregnancy. Docosahexaenoic acid
1. What is the dose of docosahexaenoic acid for lowering the cholesterol levels? Around
1.2-4 grams of docosahexaenoic acid per day reduces the levels of cholesterol in the blood.
2. Can I use docosahexaenoic acid during pregnancy? It is safe to use docosahexaenoic acid during pregnancy as per the doctor’s recommendations. It is used as an ingredient in some supplements for pregnant women.
3. What is the effect of docosahexaenoic acid in diabetic patients? Docosahexaenoic acid can increase the glucose levels in diabetics. Therefore, a cautious use is required for such patients.
4. What are the natural sources of docosahexaenoic acid? Docosahexaenoic acid is present in herring, tuna, salmon, cod liver, and meat of cold-water fish.
5. What are the side effects of fish oil containing docosahexaenoic acid? Fish oil containing docosahexaenoic acid can lead to side effects such as fishy taste, belching, loose stools and nosebleeds. Eicosapentaenoic acid
1. What is the safe dose of eicosapentaenoic acid per day? The maximum safe quantity of eicosapentaenoic acid is 3 grams per day. Beyond this amount, it can increase the risk of bleeding.
2. How can I reduce the side effects with eicosapentaenoic acid? Eicosapentaenoic acid taken with meals can reduce the side effects of the drug.
3. What happens if eicosapentaenoic acid is taken along with anti-hypertensive medicines? Eicosapentaenoic acid, when taken together with anti-hypertensive medicines, can decrease the blood pressure excessively which can be undesirable.
4. Can I take blood-thinning agents along with eicosapentaenoic acid? Due to the increased risk of bleeding, consult a doctor before taking these medicines together.
5. What is the dose of eicosapentaenoic acid for depression? The usual dose of eicosapentaenoic acid in the treatment of depression is 1 gram, twice daily.
6. How long is the treatment of menopause with eicosapentaenoic acid? It takes about 8 weeks for relieving the symptoms of menopause, with eicosapentaenoic acid 500 mg, taken thrice daily. Boron
1. Is boron safe for children? No, boron should not be used in the children younger than 12 years of age.
2. Can I take boron in the condition of fever? No, boron further raises the body temperature.
3. Does boron damage kidneys? Prolonged use of boron may cause acute tubular necrosis, oliguria, and anuria. Use the drug exactly as prescribed by the doctor.
4. What are the dosage recommendations for boron? The dosage of boron depends on the site of application and severity of the condition. Talk to the doctor before taking the drug.
5. Is boron used for diaper rash? Yes, boron is used against diaper rash. Folic acid
1. Is it necessary to take folic acid supplements during pregnancy? Yes, folic acid supplements prevent the neural tube defects in the fetus and enhance the development of the brain in the fetus. However, consult your physician to know the right dose and for the safe use of the drug.
2. Is folic acid used for the treatment of anemia? Yes. Folic acid plays a role in the formation of new red blood cells and is used for the treatment folic acid deficiency anemia.
3. Which food substances are the rich sources of folic acid? Spinach, broccoli, pulses and sunflower seeds are the rich sources of folic acid.
4. Can I take any other medications along with folic acid supplements? You must discuss with your doctor before taking any other medications
5. How should I take folic acid supplements? You should take folic acid supplements every day after meals. Follow the instructions given by your physician or the manufacturer for safe use. Methylcobalamin
1. What dietary restrictions should I follow while taking vitamin B12 supplements? You should avoid drinking alcohol while taking vitamin B12 supplements.
2. Is it safe to give vitamin B12 supplements for children? Yes, vitamin B12 supplements are safe for children. They are prescribed for the treatment of pernicious anemia and vitamin B12 deficiency in the infants and children.
3. Can I take vitamin B12 supplements during pregnancy? Yes, you can take vitamin B12 supplements during pregnancy as it promotes the growth of red blood cells in the mother and fetus.
4. Should I undergo any test while taking vitamin B12 supplements? Vitamin B12 supplements may decrease potassium levels in patients with severe vitamin B12 deficiency.
5. Can I take any other medications along with vitamin B12 supplements? You must discuss with your doctor before taking any other medications.