Trimetazidine is prescribed for the long-term treatment of angina pectoris. Additionally, it is used to control and prevent severe chest pain. Trimetazidine is also used for ear problems (ringing in the ears).
Mode of drug action :
Trimetazidine is an anti-anginal metabolic agent. It inhibits 3-ketoacyl CoA thiolase activity and reduces the oxidation of fatty acids and stimulates glucose oxidation. Stimulation of glucose oxidation leads to coupling of glycolysis and decrease in proton production. This activity will alter the overload of sodium and calcium levels in heart and decrease the cardiac efficiency during reperfusion.
What are the common side effects?
The common side effects reported with trimetazidine are hypotension, pale or redskin, palpitations, dizziness, headache, inflammation, and abnormal blood count.
Pregnancy: Safe under medical guidance Breast feeding: Unsafe
Special precautions for safe use
• Before taking Cardimax SR, inform the doctor regarding the current health conditions (if present) like allergies, vitamin deficiency etc.
• Discontinue the drug if the condition does not recover in 3 months.
• Avoid driving and operating heavy machinery.
• Inform the doctor immediately if any side effects are seen.
• Patients with kidney problems, especially elderly should exercise with caution while on Cardimax SR.
What else should I know?
1. When should I take Trimetazidine? Trimetazidineshould be taken after food with a glass full of water.
2. Is trimetazidine an addictive? No, trimetazidine does not show any addiction properties.
3. How long should I take trimetazidine medicine? Talk to you doctor and seek necessary information about the usage of the trimetazidine drug. Do not self-medicate.
4. Is trimetazidine safe during lactation? Trimetazidine is contraindicated during breastfeeding. Discuss with the doctor before taking the trimetazidine medicine.
5. What are the storage conditions for trimetazidine? Trimetazidine should be stored below 30°C.