Cledomox 312.5 MG Tablet Dt 6
Amoxicillin Amoxicillin is one amongst the penicillin group of antibiotics which is prescribed for the treatment of bacterial infections. Amoxicillin present in the drug is of great benefit for tonsil pain relief, treatment for sinus infection, genital and urinary tract infection, teeth and gum infections, respiratory tract infections, and it is a common antibiotic for many more bacterial infections. Potassium clavulanate Potassium clavulanate is widely used to treat the common bacterial infections, respiratory tract infections, and urinary tract infections. Potassium clavulanate is also prescribed during the myeloablative therapy followed by bone marrow transplantation.
Mode of drug action :
Amoxicillin Amoxicillin interferes with the production of the bacterial cell wall; it weakens and ruptures the cell wall of the bacteria thereby killing them. Beta-lactamase is a protein secreted by few bacteria which can make them resistant to some antibiotics such as penicillin/cephalosporin. Potassium clavulanate Potassium clavulanate irreversibly inactivates a wide variety of beta-lactamases, thereby making the penicillin/cephalosporin drugs more potent.
What are the common side effects?
Amoxicillin The common side effects associated with amoxicillin include nausea and vomiting, headache, allergic reaction, rash, diarrhea, stomach pain, vaginal itching, and vaginal discharge. Potassium clavulanate The common side effects associated with Potassium clavulanate are increased transaminase level in the blood, maculopapular rash, urticaria, diarrhea, and fever.
Pregnancy: Safe under medical guidance Breast feeding: Safe under medical guidance Alcohol: Unsafe Kidney dysfunction: Caution required Liver dysfunction: Caution required
Special precautions for safe use
• Avoid the drug Cledomox DT if allergic to amoxicillin or potassium clavulanate or any other penicillin.
• Avoid stomach upset by taking Cledomox DT medicine with food.
• Do not panic if loose stools are noticed. Diarrhea is one among Cledomox DT side effects, which gets better once the course is finished. If the condition worsens, consult the doctor.
• Maintain a minimum of 4 hours lag between each Cledomox DT dosage. Do not take two doses in 1 hour.
• Do not stop Cledomox DT medication in the middle of the treatment; even if the symptoms reside. start feeling better.
• Do not take the medicine Cledomox DT for more than two weeks.
• Consult your doctor before taking Cledomox DT if pregnant or breastfeeding.
What else should I know?
1. Is amoxicillin safe for children? Yes, amoxicillin is safe for children when taken in the prescribed dose. Amoxicillin dosage for children differs from that of adults.
2. Can I take amoxicillin for a sore throat, cold, cough, and flu? Amoxicillin is only effective against bacterial infections, not viruses. A sore throat, cold, and cough caused due to bacteria can be treated with amoxicillin, but the flu cannot be treated as it is a viral infection.
3. Does amoxicillin cause constipation? No. Amoxicillin does not cause constipation. Consult your doctor if you notice such side effects.
4. How long does amoxicillin take to work? The time taken for the amoxicillin to show its action may depend on the type and severity of the infections. However, it would take anywhere between one to seven days.
5. Does amoxicillin act against anaerobic bacteria? Yes. Amoxicillin is active against both aerobic as well as anaerobic bacterial infections. Potassium clavulanate
1. Why is Potassium clavulanate combined with amoxicillin? Potassium clavulanate when combined with the drug amoxicillin helps in improving its potency by preventing degradation of the drug.
2. Is Potassium clavulanate used only in combination with amoxicillin? No, Potassium clavulanate is also used in combination with other penicillin’s and cephalosporins such as cefixime.
3. Does Potassium clavulanate cause diarrhea? Yes, one of the side effects of Potassium clavulanate is diarrhea.
4. How does Potassium clavulanate help to improve the potency of amoxicillin? Potassium clavulanate is a β-lactamase inhibitor a protein secreted by the bacteria to destroy amoxicillin. By destroying this protein, it improves the potency by preventing the degradation of the drug.
5. Is Potassium clavulanate an anti-biotic itself? Yes, Potassium clavulanate, when administered alone, has weak antibacterial activity against most organisms.