Saxagliptin is an oral antidiabetic drug. It is used for the management of type 2 diabetes mellitus by controlling the blood sugar levels. Metformin hydrochloride is an oral antihyperglycemic drug which helps to reduce blood sugar levels. It is mainly prescribed for the management of type 2 diabetes. It is prescribed either as mono therapy or in combination with other antihyperglycemic drugs. It helps to prevent kidney damage, blindness, and nerve disorders in the diabetic patients. It is also prescribed during the treatment of polycystic ovarian syndrome.
How does the drug work?
Saxagliptin increases the production of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) hormones. These hormones stimulate the production of insulin to reduce blood glucose levels. Metformin is an antihyperglycemic agent which is mainly used to treat hyperglycemia. It reduces blood glucose levels by decreasing the glucose absorption from the gastrointestinal tract, improving the insulin sensitivity by increasing the uptake of glucose into muscle, and inhibiting the biosynthesis of glucose from amino acids.
What are the common side effect?
The common side effects of saxagliptin are hypoglycemia, urinary tract infections, shortness of breath, runny nose, sore throat, fatigue, blurred vision, and dizziness. The common Gluconorm SR side effects are acidity, belching, bloating, heart burn, loss of appetite, metallic taste in mouth, vomiting, weight loss, and stomach pain.
Important Information for use
• People with bone marrow depression should not use Zepcar CR medicine.
• Avoid the Zepcar CR drug if an allergic reaction was seen with an earlier use of carbamazepine.
• Do not take any other antidepressant drugs along with Carbafen tablet. If a MAO-inhibitor drug was used in the past 14 days, then do not take Zepcar CR.
• Call the doctor immediately in the case of skin rash, unusual weakness, bleeding and fever. This is because of the chances of Carbafen side effects such as life-threatening skin rash.
• Continue the Zepcar CR medication for the full length prescribed by the doctor.
• Pregnant women should not start or stop using Zepcar CR unless instructed by the doctor.
• Don’t get exposed to sunlight due to the risk of sunburn with Zepcar CR.
• Do not take grapefruit juice while using Zepcar CR.
1. Is there any important information to be followed while taking onglyza? Onglyza can be effective only when you follow recommended dietary instructions, perform exercise, and maintain normal weight.
2. Is saxagliptin safe? Yes. Saxagliptin is safe if you take in recommended doses. However, like any other drug, side effects are commonly seen. Hypoglycemia, a serious side effect can occur in some patients. Hypoglycemia is characterized by sweating, confusion, dizziness, and headache. Consult your doctor immediately if you develop any such symptoms.
3. Does onglyza have metformin in it? No. Onglyza contains a single active ingredient ‘saxagliptin’.
4. What is the best time to take saxagliptin tablets? Saxagliptin tablets can be taken at any time of the day but make sure that you are taking at the same time every day.
5. What should I do if I experience any of the side effects of onglyza? Stop the medication and consult your doctor immediately. Your doctor may change the saxagliptin dose depending on your physical condition. Metformin
1. What should I do if I miss a dose? If you forget to take the medication at the usual time, you must take it as soon as you remember. If it is time for the next dose, you must skip the missed dose. Do not take a double dose.
2. Are there any storage precautions for metformin? Store the medication at room temperature (25°C) and away from direct heat. Keep the drug out of reach of children.
3. Should I take vitamin B12 supplements with metformin? Long term use of metformin may cause vitamin B12 deficiency in few patients. You should consult your doc-or and discuss it. Do not take vitamin B12 supplements without your physician’s prescription.
4. Is metformin effective for the type 1 diabetes? No. Metformin is not effective for the treatment of type 1 or juvenile diabetes
5. What are the non-diabetic uses of metformin? Metformin is used to treat PCOS in women. You must discuss with your doctor before taking metformin for the condition.