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Aspirin is an analgesic, used to relieve moderate to severe pain, such as headache, migraine, nerve pain, toothache, sore throat, joint pain, dysmenorrhea (pain during periods) and heart attack. It is also used as a blood thinner in heart diseases and stroke. Atorvastatin uses include regulation of the fat levels in the body along with the diet and lifestyle changes . It lowers the cholesterol levels and is useful for patients with a high risk of heart diseases. Clopidogrel is used to prevent blood from clotting. Clopidogrel is beneficial in the prevention of heart attack and stroke, and relieve chest pain.
How does the drug work?
two chemicals- prostaglandins and thromboxanes. Low levels of prostaglandin bring about pain relief. Low thromboxane levels results in thinning of blood, therefore, its long-term use helps to prevent heart attack and stroke. Atorvastatin acts by inhibiting an enzyme called HMG-CoA reductase which is involved in the synthesis of cholesterol in the liver. It also increases the breakdown of the cholesterol by enhancing its uptake by the liver cells. Clopidogrel is an anti-platelet drug. The drug works by preventing platelets (a type of blood cells) from aggregating, thereby, preventing the formation of blood clots. Clopidogrel is also known as a blood-thinning agent as it keeps the blood thin enough to flow smoothly through the blood vessels.
What are the common side effect?
The common side effects of aspirin include rashes, ulcers in the gastrointestinal tract, stomachache, abdominal cramping, nausea, heartburn, drowsiness, headache, and bleeding. The commonly experienced atorvastatin side effects are diarrhea, nausea, indigestion, pain in the extremities, urinary tract infections, inflammation of the nasal passages, pain in the throat, nose bleed, joint pain, muscle pain and back pain, liver function abnormalities, and sleep disorders. The common side effects of clopidogrel include diarrhea, nausea, acne-like rash, joint pain, chest pain, headache, upper respiratory tract infection, urinary tract infection, depression, and bruising.
Important Information for use
• People with bone marrow depression should not use Zepcar CR medicine.
• Avoid the Zepcar CR drug if an allergic reaction was seen with an earlier use of carbamazepine.
• Do not take any other antidepressant drugs along with Carbafen tablet. If a MAO-inhibitor drug was used in the past 14 days, then do not take Zepcar CR.
• Call the doctor immediately in the case of skin rash, unusual weakness, bleeding and fever. This is because of the chances of Carbafen side effects such as life-threatening skin rash.
• Continue the Zepcar CR medication for the full length prescribed by the doctor.
• Pregnant women should not start or stop using Zepcar CR unless instructed by the doctor.
• Don’t get exposed to sunlight due to the risk of sunburn with Zepcar CR.
• Do not take grapefruit juice while using Zepcar CR.
1. How often should I take Aspirin? It is best to take aspirin as directed by your physician. Usually, the drug is taken daily, for its maximum benefit.
2. Are there any risks associated with aspirin? Yes, aspirin may increase the risk of bleeding. So if you already have a bleeding disorder, you may need to take aspirin in reduced doses or under medical supervision. The drug may also increase the risk of stomach ulcers; therefore, those with the history of ulcers should be careful.
3. What can I do to prevent stomach upset associated with the Aspirin intake? Stomach upset is a common side-effect of Aspirin and may decrease once the body gets used to the drug. Taking the medication with milk or after food reduces stomach upset.
4. Can I give aspirin for the treatment of fever in my 7-year-old child? No, aspirin can cause Reye’s syndrome, a serious illness, in children; therefore, it should be avoided for this age group.
5. I am scheduled for a surgery after a month. Should I tell my surgeon that I take aspirin? Yes, you should tell your surgeon that you take aspirin. Aspirin may increase the risk of bleeding during or after surgery. Therefore the medication must be stopped for a week or two before the surgery, to reduce the bleeding risk. Atoravastatin:
1. Is breast enlargement in men a side effect of atorvastatin? Breast enlargement in men also called, gynecomastia is a very rare side effect of atorvastatin.
2. Can I use atorvastatin for coronary heart disease prevention? Atorvastatin is a treatment to lower bad cholesterol. Therefore, you can use this medicine for heart disease prevention only with a doctor’s advice.
3. Can atorvastatin reduce my risk of heart attack? Yes. Atorvastatin is routinely prescribed as a part of treatment to reduce heart attack risk.
4. What is the initial atorvastatin dose for children aged above 10 years? The starting dose of atorvastatin for children above 10 years is usually 10 mg, once daily. However, the dosage of the drug depends on the severity of the condition which is decided by the physician.
5. What is the maximum dose in the safe use of atorvastatin in children? The maximum safe dose of atorvastatin used for children is usually 20 mg per day. Clopidogrel:
1. I have stomach ulcer which causes bleeding at times, can I use clopidogrel bisulfate? No, if you have any bleeding diseases, then you should not use clopidogrel bisulfate as it can cause bleeding.
2. I am on clopidogrel since two months; can I undergo a dental surgery? If you are planning to undergo any surgery, you must make the doctor aware that you are using clopidogrel bisulfate, because it may cause over bleeding during the surgical procedure.
3. What are the suitable storage conditions for clopidogrel bisulfate? Clopidogrel bisulfate must be stored at a room temperature away from moisture and heat.
4. Can I gain or lose weight by chronic use of clopidogrel bisulfate? No, there is no evidence that you may lose or gain weight with the long-term use of clopidogrel bisulfate.
5. I have gastric acidity problem and am on clopidogrel. Is it ok if I administer ranitidine for acidity? Yes, ranitidine is safe to take with clopidogrel. But other drugs of same class such as cimetidine which are used in gastric acidity can interact with clopidogrel.