Midiclo 50/200 Mg Tablet 6
Diclofenac is used for stiffness, swelling, and joints pain caused by arthritis. It is also used for the acute and chronic treatment of symptoms of osteoarthritis. Diclofenac is used as an analgesic in some minor surgeries such as dental. Misoprostol is used in combination with another drug such as mifepristone to avoid pregnancy. It is also used to prevent stomach ulcers especially while taking NSAID’s. It is also used to reduce the serious ulcer complications such as bleeding. Misoprostol also protects stomach lining by lowering the amount of acid production.
How does the drug work?
Diclofenac is a NSAID used to reduce inflammation and pain. The anti-inflammatory effects are due to the inhibition of cyclooxygenase (COX-1 and COX-2). This, in turn, inhibits the prostaglandin synthesis. Inhibition of the prostaglandin synthesis results in the analgesic effects of diclofenac. Misoprostol inhibits gastric acid secretion by acting directly on prostaglandin receptor of parietal cells. It indirectly inhibits adenylate cyclase mediated by G proteins. This significant action of misoprostol is related to several mechanisms of the body such as increased secretion of bicarbonate, replacement of prostaglandins etc. it is increases the frequency and amplitude of uterine contractions.
What are the common side effect?
The common side effects of diclofenac are stomach upset, constipation, discomfort, drowsiness, decrease in urine output, increased bleeding time, weight loss, itching of skin, epidermal necrolysis, kidney dysfunction. The commonly known side effects of misoprostol are nausea, stomach cramps, dehydration, dizziness, decreased urination, mental or mood changes, muscle weakness, and slow or irregular heartbeat.
Important Information for use
• People with bone marrow depression should not use Zepcar CR medicine.
• Avoid the Zepcar CR drug if an allergic reaction was seen with an earlier use of carbamazepine.
• Do not take any other antidepressant drugs along with Carbafen tablet. If a MAO-inhibitor drug was used in the past 14 days, then do not take Zepcar CR.
• Call the doctor immediately in the case of skin rash, unusual weakness, bleeding and fever. This is because of the chances of Carbafen side effects such as life-threatening skin rash.
• Continue the Zepcar CR medication for the full length prescribed by the doctor.
• Pregnant women should not start or stop using Zepcar CR unless instructed by the doctor.
• Don’t get exposed to sunlight due to the risk of sunburn with Zepcar CR.
• Do not take grapefruit juice while using Zepcar CR.
1. What are the different dosage forms available for diclofenac other than tablet form? Diclofenac is available in different forms such as injectables, topical applicators (powder or ointment), and capsule form.
2. Is there any alteration in weight with the use of diclofenac tablet? You may have a reduced weight, because of loss of appetite which is one of the common diclofenac side effects.
3. What are the symptoms of overdose? You may have blurred vision, altered consciousness, confusion, depression in the case of an overdose with diclofenac. To avoid these side effects use the medicine as directed by the doctor.
4. Is diclofenac safe for children below 12 years of age? No, it is not recommended to give diclofenac tablet for children younger than 18 years of age.
5. What should I avoid when using diclofenac medicine? Avoid using other NSAID’s. Do not drink alcohol. Do not use diclofenac if you are allergic to it. Misoprostol:
1. Does misoprostol cause unwanted hair growth? Yes, misoprostol has androgenic side effects such as unwanted hair growth in females.
2. Does misoprostol delay periods? Yes, your period is delayed beyond the date you expected your period when you take misoprostol.
3. Can I use misoprostol as a routine contraceptive? No. It is not recommended to use as a routine contraceptive pill. It is only an emergency contraceptive pill.
4. Is misoprostol used to treat acne? No, in fact, it causes acne as a side-effect.
5. Is misoprostol an over-the-counter (OTC) drug? It is available both as OTC and prescription drug. Do not use this drug without consulting your doctor.